Daniel Mulkerin Selected Research

1,24-dihydroxyvitamin D2

12/2015

A phase I study to determine the maximum tolerated dose and safety of oral LR-103 (1α,24(S)Dihydroxyvitamin D2) in patients with advanced cancer.

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Daniel Mulkerin Research Topics

Disease

9	Neoplasms (Cancer) 10/2017 - 11/2002
4	Colorectal Neoplasms (Colorectal Cancer) 06/2012 - 01/2002
3	Adenocarcinoma 06/2012 - 01/2005
2	Breast Neoplasms (Breast Cancer) 10/2017 - 12/2010
2	Fatigue 12/2015 - 01/2002
2	Liver Diseases (Liver Disease) 05/2012 - 08/2003
2	Carcinoma (Carcinomatosis) 09/2011 - 01/2005
1	Disease Progression 10/2017
1	Death (Near-Death Experience) 10/2017
1	Colonic Neoplasms (Colon Cancer) 09/2016
1	Urinary Tract Infections (Urinary Tract Infection) 12/2015
1	Neuroendocrine Carcinoma 01/2011
1	Pancreatic Neoplasms (Pancreatic Cancer) 06/2008
1	Hepatocellular Carcinoma (Hepatoma) 01/2008
1	Dyspnea (Shortness of Breath) 01/2008
1	Diarrhea 01/2008
1	Esophageal Neoplasms (Esophageal Cancer) 01/2005
1	Squamous Cell Carcinoma (Epidermoid Carcinoma) 01/2005
1	Neoplasm Metastasis (Metastasis) 08/2003
1	Lymphoma (Lymphomas) 11/2002
1	Eructation (Eructations) 01/2002
1	Vomiting 01/2002
1	Nausea 01/2002
1	Anorexia 01/2002

Drug/Important Bio-Agent (IBA)

4	Oxaliplatin (Eloxatin)FDA LinkGeneric 06/2012 - 07/2003
3	Gemcitabine FDA Link 06/2008 - 11/2002
2	Bortezomib (Velcade)FDA Link 05/2012 - 12/2011
2	PlatinumIBA 09/2011 - 08/2003
2	CreatinineIBA 01/2008 - 08/2003
1	Biomarkers (Surrogate Marker)IBA 09/2016
1	Vitamin D FDA LinkGeneric 12/2015
1	Alkaline PhosphataseIBA 12/2015
1	1,24-dihydroxyvitamin D2IBA 12/2015
1	Tyrosine Kinase InhibitorsIBA 06/2012
1	Monoclonal AntibodiesIBA 06/2012
1	Capecitabine (Xeloda)FDA Link 06/2012
1	Irinotecan (Camptosar)FDA LinkGeneric 06/2012
1	Lapatinib (GW572016)FDA Link 06/2012
1	Cisplatin (Platino)FDA LinkGeneric 09/2011
1	Carboplatin (JM8)FDA LinkGeneric 09/2011
1	satraplatin (JM 216)IBA 09/2011
1	Valproic Acid (Depakote)FDA LinkGeneric 01/2011
1	Zoledronic Acid (Zometa)FDA Link 12/2010
1	lestaurtinibIBA 06/2008
1	Insulin-Like Growth Factor I (IGF-1)IBA 01/2008
1	Insulin-Like Growth Factor II (Somatomedin A)IBA 01/2008
1	Growth Hormone (Somatotropin)IBA 01/2008
1	Octreotide (Sandostatin)FDA LinkGeneric 01/2008
1	Biological ProductsIBA 01/2008
1	Leucovorin (Folinic Acid)FDA Link 01/2005
1	Fluorouracil (Carac)FDA LinkGeneric 01/2005
1	Pharmaceutical PreparationsIBA 08/2003
1	eniluracilIBA 11/2002
1	perillyl alcoholIBA 01/2002

Therapy/Procedure

7	Drug Therapy (Chemotherapy) 10/2017 - 08/2003
4	Therapeutics 10/2017 - 01/2002
1	Liver Transplantation 08/2003